Herpes simplex type 1 encephalitis in acquired immunodeficiency syndrome.

Tan, S V; Guiloff, R J; Scaravilli, F; Klapper, P E; Cleator, G M; Gazzard, B G · Ann Neurol · 1993

case_report · Level V

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Abstract

A severe acute necrotizing herpes simplex virus type 1 encephalitis, apparently mediated by macrophages or cytokines or both, was seen in a patient with acquired immunodeficiency syndrome. The necrosis had a distribution similar to that seen in immunocompetent subjects. Viral inclusions were abundant and meningeal reaction was minimal, as previously described in one anergic patient.

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