Myasthenia gravis and scleroderma.

Bhalla, R; Swedler, W I; Lazarevic, M B; Ajmani, H S; Skosey, J L · J Rheumatol · 1993

case_report · Level V

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Abstract

Myasthenia gravis is an autoimmune disease that is associated with antibodies to acetylcholine receptors. It is associated with other autoimmune diseases such as thyroiditis (10%), systemic lupus erythematosus (2-8%), rheumatoid arthritis (4-7%), Sjögren's syndrome and polymyositis. It is not commonly found with scleroderma. We describe a case of scleroderma developing in a patient 6 years after the onset of myasthenia gravis. HLA-B8/DR3 may play a role in the association of the 2 conditions.

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