Bromocriptine-induced dystonia in patients with aphasia and hemiparesis.

Leiguarda, R; Merello, M; Sabe, L; Starkstein, S · Neurology · 1993

case_series · Level IV

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Abstract

Five of seven patients with chronic nonfluent aphasia and hemiparesis due to a focal ischemic infarction developed painful hemidystonia during treatment with a high dose of bromocriptine. All seven patients had cortical damage, but four also had basal ganglia and one thalamic involvement. While lesion location did not differ between dystonic and nondystonic patients, the dystonic patients had more weakness than those without dystonia.

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