Relationship between radiobiological hypoxia and direct estimates of tumour oxygenation in a mouse tumour model.
basic_science · Level V
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Abstract
CDF1 mice were allowed to breathe either oxygen, carbogen or different concentrations of carbon monoxide gas. These treatments significantly altered the percentage of clonogenic hypoxic cells in a C3H mouse mammary carcinoma and these changes were found to correlate with direct measurements of tumour oxygenation obtained using an Eppendorf pO2 electrode.
Medical subject headings
- Mammary Neoplasms, Experimental
- Oxygen