A case of Satoyoshi's syndrome.

Abstract

Satoyoshi's syndrome is a rare neurologic disorder characterized by progressive muscle spasms, alopecia, diarrhea, and skeletal abnormalities. We describe a 21-year-old woman with Satoyoshi's syndrome whose skeletal changes were followed for 15 years until after she had reached skeletal maturity. The patient developed slipping of the epiphyses in the proximal humeri and femurs and metaphyseal lesions mimicking metaphyseal chondrodysplasia. These lesions were a consequence of physeal injuries caused by the recurrent muscle spasms.