Prepubescent pituitary null cell macroadenoma with silent macroscopic apoplexy: case report.
case_report · Level V
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Abstract
Secreting pituitary adenomas have marked prevalence in pediatric adenomas. We described a case of an 11-year-old boy with pituitary null cell macroadenoma with silent macroscopic pituitary apoplexy. The patient was admitted with bitemporal hemianopsia and a gradual deterioration of visual acuity. An endocrinological study revealed a low concentration of testosterone and in the plasma a decreased response of luteinizing hormone and follicle-stimulating hormone to luteinizing hormone-releasing hormone. This patient may be the first case of prepubescent null cell macroadenoma confirmed with immunohistochemical study in addition to the findings of classical histopathology.
Medical subject headings
- Adenoma, Chromophobe
- Pituitary Apoplexy
- Pituitary Neoplasms