Positron emission tomography with fluorine-18-fluorodeoxyglucose for the evaluation of therapeutic isolated regional limb perfusion in a patient with soft-tissue sarcoma.
case_report · Level V
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Abstract
The treatment of a patient with soft-tissue sarcoma was evaluated with FDG-PET. A limb-saving complete remission of a locally advanced liposarcoma of the left thigh was achieved with isolated regional perfusion of the limb with tumor necrosis factor alpha, interferon gamma and melphalan. PET with 18F-FDG before perfusion showed high glucose consumption in the tumor. After perfusion, glucose metabolism in the tumor was absent. Subsequent excision confirmed complete necrosis of the tumor. FDG-PET may be useful in evaluating the results of isolateral regional limb perfusion for soft-tissue sarcomas.
Medical subject headings
- Chemotherapy, Cancer, Regional Perfusion
- Deoxyglucose
- Leg
- Liposarcoma
- Soft Tissue Neoplasms
- Tomography, Emission-Computed