Regional myocardial ischaemia and diastolic dysfunction in hypertensive heart disease.
review · Level V
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Abstract
In patients with systemic hypertension there is progressive left ventricular remodelling characterized mainly by left ventricular hypertrophy accompanied by abnormal diastolic ventricular function. Regional ischaemia, secondary to abnormal myocardial perfusion may explain in part the decrease in relaxation and compliance of the hypertrophied left ventricle. Treatment with anti-ischaemia drugs, such as beta-blockers or calcium channel blockers, improve left ventricular diastolic function.
Medical subject headings
- Hypertension
- Hypertrophy, Left Ventricular
- Myocardial Ischemia