Misalignment of pulmonary veins with alveolar capillary dysplasia: affected siblings and variable phenotypic expression.

Boggs, S; Harris, M C; Hoffman, D J; Goel, R; McDonald-McGinn, D; Langston, C; Zackai, E; Ruchelli, E · J Pediatr · 1994

case_report · Level V

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Abstract

Misalignment of pulmonary veins with alveolar capillary dysplasia is recognized as a rare cause of persistent pulmonary hypertension of the neonate. Until now, misalignment of pulmonary veins was thought to be a random occurrence, but its appearance in siblings at our institution suggests that there may be a familial predisposition. There have been reports of variable expression and variable severity in this disease; our report describes this variability in family members.

Medical subject headings