Recombinant interferon-alpha efficacy in relapsed adult nephroblastoma: a case report.
case_report · Level V
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Abstract
We report on a 37-year-old woman with progressive lung and pleural metastases from a right nephroblastoma, who achieved partial remission with recombinant interferon-alpha. The drug was given subcutaneously at a dose of 5 mu. 3 times per week. The response was documented after 3 months of treatment and was maintained for at least 9 months. Although such a response has not been reported in the literature, this case suggests promising activity of recombinant interferon-alpha in relapsed nephroblastoma.
Medical subject headings
- Interferon-alpha
- Kidney Neoplasms
- Neoplasm Recurrence, Local
- Wilms Tumor