Folliculitis in Down's syndrome.

Kavanagh, G M; Leeming, J P; Marshman, G M; Reynolds, N J; Burton, J L · Br J Dermatol · 1993

case_series · Level IV

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Abstract

Twenty-two male and 20 female adults with Down's syndrome were examined. Ten of the men and two of the women had a follicular rash consistent with Malassezia folliculitis. Oral itraconazole treatment produced a significant improvement in the rash, accompanied by a decrease in the skin Malassezia count. Clinical relapse occurred when therapy was discontinued, and was accompanied by return of the Malassezia yeasts.

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