The mammalian Na+/H+ exchanger gene family--initial structure/function studies.

Tse, M; Levine, S; Yun, C; Brant, S; Pouyssegur, J; Donowitz, M · J Am Soc Nephrol · 1993

editorial · Level V

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Abstract

A gene family of mammalian Na+/H+ exchangers has been identified. Three isoforms have been cloned, sequenced, and stably expressed, and structure/function studies have been begun. Several of the isoforms are found in the epithelia, and one of them is epithelial specific.

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