Magnetic resonance evaluation of disease activity during pregnancy in multiple sclerosis.

van Walderveen, M A; Tas, M W; Barkhof, F; Polman, C H; Frequin, S T; Hommes, O R; Valk, J · Neurology · 1994

case_series · Level IV

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Abstract

We followed two women with MS during pregnancy by means of serial unenhanced MR imaging. On each follow-up image, we assessed the number of new or enlarging lesions. Both women showed a decrease in MR disease activity during the second half of pregnancy and a return of MR disease activity to prepregnancy levels in the first months postpartum. These findings support the view that pregnancy reduces disease activity in MS.

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