Zidovudine plus interferon alfa-2b treatment in patients with HIV and chronic active viral hepatitis.
case_series · Level IV
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- Record sourced from PubMed, PMID 8314472.
- Also identified by PMC identifier 1374028.
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Abstract
Results are reported for a small study of 11 patients positive for HIV and with chronic active viral hepatitis. Low dose zidovudine/interferon alfa-2b combined treatment produced a general reduction in alanine aminotransferase activities and increased the CD4 lymphocyte count, hepatitis B e seroconversion, and the loss of HIV p24 antigen. The treatment was well tolerated and progression of HIV disease was not seen.
Medical subject headings
- HIV Infections
- Hepatitis, Chronic
- Interferon-alpha
- Zidovudine