Efficacy of different regimens of interferon alfa-2b treatment in chronic hepatitis C.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 8314480.
- Also identified by PMC identifier 1374040.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Four different dosage regimens of interferon (IFN) alfa-2b (3 million units (MU) three times weekly for three months, 3 MU three times weekly for six months, 6 MU two times weekly for six months, and 6 MU three times weekly for six months) were compared in patients with chronic hepatitis C. There was no significant difference measured by percentage of responders to treatment between the four groups, but the degree of response was inversely correlated with the severity of liver damage. Viraemia was undetectable in most (75%) of responders treated with interferon and also in 20% of those who did not respond to treatment.
Medical subject headings
- Hepatitis C
- Hepatitis, Chronic
- Interferon-alpha