Alpha interferon treatment of chronic hepatitis C in beta-thalassaemia.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 8314484.
- Also identified by PMC identifier 1374044.
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Abstract
In this open, pilot study, interferon (IFN) alpha-2b seemed effective in the treatment of hepatitis C virus (HCV) infection in patients with beta-thalassaemia. In seven of nine patients who completed the study alanine aminotransferase activities returned to normal, and a completely stable response 24 months after treatment was seen in five. Liver biopsy specimen showed a clear reduction in portal, periportal, and lobular necroinflammation in all five cases. Three patients stopped treatment early because of side effects.
Medical subject headings
- Hepatitis C
- Interferon-alpha
- beta-Thalassemia