Effect of age on the sensitivity of upper airway reflexes.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 8318333.
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Abstract
We have recorded the threshold concentration of inhaled ammonia vapour required to elicit reflex glottic closure (NH3TR) in 102 healthy, nonsmoking volunteers (39 female) aged 17-96 yr in order to assess the effect of age upon upper airway reflex sensitivity. A single measurement of sensitivity was made in each subject using a system delivering small concentrations of ammonia vapour for single intermittent breaths to the upper airway and recording glottic closure using an inspiratory pneumotachograph. We found a strong positive correlation between age and NH3TR, indicating a decrease in upper airway reflex sensitivity with increasing age.
Medical subject headings
- Aging
- Glottis
- Larynx
- Reflex