Severe vascular toxicity associated with cisplatin-based chemotherapy.

Içli, F; Karaoğuz, H; Dinçol, D; Demirkazik, A; Günel, N; Karaoğuz, R; Uner, A · Cancer · 1993

case_report · Level V

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Abstract

A 19-year-old man with a germ cell tumor who experienced hypertension, acute myocardial infarction, and cerebrovascular accident (CVA) associated with hypomagnesemia as late complications of cisplatin-based chemotherapy is presented, and previously reported cases in the literature are reviewed. Different physiopathologic mechanisms are hypothesized for early and late vascular complications of cisplatin.

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