Psychological stress as risk factor for exacerbations in multiple sclerosis.

Nisipeanu, P; Korczyn, A D · Neurology · 1993

prospective_cohort · Level II

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Abstract

We prospectively evaluated the relationship between a common psychological stressor and relapses in multiple sclerosis (MS) in a group of 32 MS patients exposed to the threat of missile attacks during the Persian Gulf War of 1991. The number of relapses during the war and the following 2 months was significantly lower than expected based on the frequency during the preceding 2 years, suggesting that not all stress conditions increase the risk of exacerbations in MS.

Medical subject headings