Pharmacological study of the internal and sphincter in patients with chronic anal fissure.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 8330180.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A pharmacological study of the internal anal sphincter (IAS) was undertaken in patients with chronic and fissure. The sensitivity of the IAS to the contractile effect of phenylephrine and potassium chloride and to relaxation by isoproterenol was evaluated. Supersensitivity of the IAS to relaxation by isoproterenol was noted. Further research is necessary to determine the pharmacological basis of such a disturbance.
Medical subject headings
- Anal Canal
- Fissure in Ano
- Isoproterenol
- Phenylephrine
- Potassium Chloride