Neurological and adrenal dysfunction in the adrenal insufficiency/alacrima/achalasia (3A) syndrome.
case_series · Level IV
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- Record sourced from PubMed, PMID 8333772.
- Also identified by PMC identifier 1029374.
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Abstract
Review of 20 patients with glucocorticoid deficiency (three cases also with salt loss) associated with absent tear secretion (19 cases) and achalasia of the cardia (15 cases) revealed neurological abnormalities in 17 including hyper-reflexia, muscle weakness, dysarthria, and ataxia together with impaired intelligence and abnormal autonomic function, particularly postural hypotension. These findings indicate that significant neurological problems are common in this multisystem disorder.
Medical subject headings
- Addison Disease
- Esophageal Achalasia
- Nervous System Diseases
- Tears