Three-dimensional imaging for diagnostic ultrasound in dermatology.

Abstract

Visual examination and cutaneous biopsies, two major tools in dermatologic diagnosis, do not provide structural information regarding the entire tissue volume. Our purpose was to develop a high-resolution ultrasound system that quickly, with minimal operator interaction, displays structural data on the entire tissue volume. A prototype ultrasound B-scan system was developed and operated at nominal center frequencies between 35 and 50 MHz, with computer processing of data to produce three-dimensional images. These images displayed as three-dimensional "blocks" can be sectioned to provide multiple images of internal structure (i.e., "acoustic biopsies"). B-scans and associated three-dimensional images were obtained from assorted skin sites in selected patients. This technique provides a valuable diagnostic tool that is now being further evaluated.