A rapid test for the detection of human immunodeficiency virus antibodies in cord blood.

Suarez, M A; Blanco, B; Brion, L P; Schulman, M; Calvelli, T A; Youchah, J; Devash, Y; Rubinstein, A et al. · J Pediatr · 1993

case_control · Level III

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Abstract

A commercially available rapid test (HIVCHEK) was compared with an enzyme-linked immunosorbent assay (ELISA) for identifying human immunodeficiency virus type 1 in the serum of newborn infants. Of 1309 cord blood samples tested, the HIVCHEK test detected all the true-positive samples detected by ELISA. Of the 35 samples with positive ELISA results, six had negative results on Western blot; only 1 of the 30 samples with positive HIVCHEK results had negative results on Western blot. Thus the HIVCHEK test can be used to facilitate the rapid identification of HIV-1 in the serum of newborn infants.

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