Intracavernous sodium nitroprusside: inappropriate impotence treatment.

Brock, G; Breza, J; Lue, T F · J Urol · 1993

case_report · Level V

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Abstract

On the basis of reports describing nitric oxide as a form of endothelium-derived relaxing factor and on our own experience with intracavernous use of nitric oxide-releasing substances in animal models, we undertook an approved human study of intracavernous sodium nitroprusside as a treatment for impotence. We report our early experience in which severe hypotension and only mild tumescence in our first 3 patients caused us to discontinue the trial.

Medical subject headings