Percutaneous nephrostomy drainage in the treatment of severe hemorrhagic cystitis.
case_report · Level V
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Abstract
We report on 2 patients who underwent urinary diversion with bilateral percutaneous nephrostomy tube drainage for intractable hemorrhagic cystitis. Both patients received cyclophosphamide-based chemotherapy and 1 also underwent pelvic irradiation for locally advanced prostate adenocarcinoma. In each case the bleeding gradually ceased during a 1-week period. Both patients were alive at 6 months and were voiding spontaneously. We propose that the mechanism of treatment involves diverting endogenous urokinase as well as avoiding overdistention of the bladder.
Medical subject headings
- Cystitis
- Drainage
- Hemorrhage
- Nephrostomy, Percutaneous
- Urinary Bladder Diseases
- Urinary Diversion