Intraoperative procurement of autologous fibrin glue.

Quigley, R L; Perkins, J A; Gottner, R J; Curran, R D; Kuehn, B E; Hoff, W J; Wallock, M E; Arentzen, C E et al. · Ann Thorac Surg · 1993

case_series · Level IV

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Abstract

A method of intraoperative procurement of autologous fibrin glue is described. The relative efficacy of our autologous preparation is compared with that of fibrin glue made with homologous cryoprecipitate. Experimentally, the fibrinogen content and the strength are less than those found in cryoprecipitate and appear related to the fibrinogen content of the autologous plasma used as substrate in the fibrin glue reaction. Clinically, no significant differences are noted in the performance of autologous fibrin glue. We believe the absence of the risk of blood-borne infection with the autologous product is a major advantage.

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