Successful treatment of childhood onset symptomatic dystonia with levodopa.

Fletcher, N A; Thompson, P D; Scadding, J W; Marsden, C D · J Neurol Neurosurg Psychiatry · 1993

case_report · Level V

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Abstract

Three patients with childhood onset symptomatic dystonia responded to levodopa. None fulfilled criteria for a diagnosis of "dopa responsive dystonia" (Segawa's disease). One may have had athetoid cerebral palsy for almost 25 years. All obtained dramatic and sustained benefit from levodopa therapy. A therapeutic trial of levodopa is advised in all patients in whom dystonia has developed in childhood or early adult life, regardless of suspected aetiology or duration of symptoms.

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