Non-injection methods for the production of embryonic stem cell-embryo chimaeras.
basic_science · Level V
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Abstract
The simple aggregation of pluripotent ES cells with morulae-stage embryos can result in viable chimaeras at a similar frequency to that of blastocyst injection. The savings in time and equipment inherent in the aggregation techniques, however, make this approach well worth considering.
Medical subject headings
- Chimera
- Embryo, Mammalian
- Stem Cells