The Conneulor: unbiased estimation of connectivity using physical disectors under projection.

Gundersen, H J; Boyce, R W; Nyengaard, J R; Odgaard, A · Bone · 1993

basic_science · Level V

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Abstract

The Euler number and the connectivity of an arbitrary object is defined, and it is illustrated why the connectivity of an n-dimensional object cannot be estimated in an (n-1)-dimensional section. The disector--principle for 3-D counting of the Euler--events is illustrated in cancellous bone. The correct handling for unbiased counting of events at artificial edges is outlined. A nomogram for predicting the precision of an estimate is provided.

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