Anaphylactic reaction to ranitidine.
case_report · Level V
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- Record sourced from PubMed, PMID 8368468.
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Abstract
Ranitidine is a well-tolerated H2-receptor antagonist with a furan ring as nucleus. Anaphylactic reactions are seldom reported despite the wide use of the drug. We report a patient who presented an anaphylactic reaction with ranitidine (Zantac). The positive skin prick test and oral challenge suggest type I hypersensitivity. Specific IgE determination by RAST technique and histamine release test with ranitidine were negative. The patient did not react to other H2-receptor antagonists or to another furan-derivative (nitrofurantoin).
Medical subject headings
- Anaphylaxis
- Drug Hypersensitivity
- Ranitidine