Investigation of a biodegradable, implantable antibiotic delivery system on rate of wound infection.

Sasmor, M T; Morain, W D; Balestrero, L M; Camp, B J · Ann Plast Surg · 1993

basic_science · Level V

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Abstract

Biodel, a bioabsorbable polymer, may be adapted to serve as an antibiotic delivery system for high local concentrations of drugs. In an autocontaminated, irradiated wound model with a high intrinsic infection rate, implanted gentamicin-impregnated Biodel beads prevented wound infections in the submental area of rats.

Medical subject headings