Hydralazine predisposes to acute cutaneous vasculitis following urography with iopamidol.
case_report · Level V
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Abstract
We report a 60-year-old woman with renovascular hypertension who developed a severe cutaneous vasculitis 24 h after the injection of iopamidol during urography. A review of the literature suggests that her concomitant hydralazine therapy probably predisposed her to this reaction, as similar reactions have occurred in systemic lupus erythematosus, and hydralazine can induce a LE-like syndrome. We recommend that urography should be avoided in patients receiving hydralazine.
Medical subject headings
- Hydralazine
- Iopamidol
- Urography
- Vasculitis, Leukocytoclastic, Cutaneous