Congenital aortic stenosis and pregnancy--a reappraisal.

Lao, T T; Sermer, M; MaGee, L; Farine, D; Colman, J M · Am J Obstet Gynecol · 1993

retrospective_cohort · Level III

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Abstract

This study was performed to determine the maternal and fetal outcome in pregnant patients with congenital aortic stenosis without previous valvular replacement. A retrospective review of 25 pregnancies in 13 patients delivered at our centers from September 1976 to September 1992 was undertaken. Five (38%) patients had associated congenital heart lesions, three (23%) had severe stenosis (echocardiographically estimated valve area < or = 0.7 cm2), two had prior open aortic valve commissurotomy, and one had balloon valvuloplasty during pregnancy. There were no maternal deaths. Of the 25 pregnancies, five (20%) resulted in therapeutic abortions. There was no perinatal mortality, preterm labor, or increased incidence of pregnancy complications or fetal growth retardation in the remaining 20 pregnancies. One infant (5%) had congenital heart disease. Pregnancy outcome is generally satisfactory in patients with congenital aortic stenosis.

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