The isolation of molecular genetic markers for the identification of sex.

Griffiths, R; Tiwari, B · Proc Natl Acad Sci U S A · 1993

basic_science · Level V

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Abstract

It is difficult to identify sex in many species of eukaryotic organism. This can considerably impede research into their biology. Fortunately, one sex often possesses a unique chromosome termed Y or W. When DNA markers are available for these chromosomes, then sex identification becomes straightforward. We describe a technique that facilitates the isolation of such markers. The procedure makes use of low-stringency PCR to screen randomly selected primers for their ability to amplify sex-specific loci.

Medical subject headings