Inositol trisphosphate and calcium signalling.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 8381210.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Inositol trisphosphate is a second messenger that controls many cellular processes by generating internal calcium signals. It operates through receptors whose molecular and physiological properties closely resemble the calcium-mobilizing ryanodine receptors of muscle. This family of intracellular calcium channels displays the regenerative process of calcium-induced calcium release responsible for the complex spatiotemporal patterns of calcium waves and oscillations. Such a dynamic signalling pathway controls many cellular processes, including fertilization, cell growth, transformation, secretion, smooth muscle contraction, sensory perception and neuronal signalling.
Medical subject headings
- Calcium
- Calcium Channels
- Inositol 1,4,5-Trisphosphate
- Receptors, Cytoplasmic and Nuclear
- Second Messenger Systems
- Signal Transduction