Abnormal expression of glucose-6-phosphatase in preterm infants.
case_control · Level III
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- Record sourced from PubMed, PMID 8386919.
- Also identified by PMC identifier 1029235.
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Abstract
The hepatic microsomal glucose-6-phosphatase enzyme was studied in liver samples from 76 premature infants including 15 victims of sudden infant death syndrome. The data obtained were compared with glucose-6-phosphatase activity in liver samples from 95 term infants. In the majority of preterm infants up to 350 days of age the activity of the glucose-6-phosphatase enzyme was at or below the extreme low limit of the normal range in term infants. The premature infants with the lowest hepatic microsomal glucose-6-phosphatase activities are likely to be at risk of hypoglycaemic episodes during periods of relative starvation or stress.
Medical subject headings
- Glucose-6-Phosphatase
- Infant, Premature, Diseases
- Microsomes, Liver