Detection of HCV-RNA in saliva of patients with chronic hepatitis C.
case_series · Level IV
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- Record sourced from PubMed, PMID 8390957.
- Also identified by PMC identifier 1374010.
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Abstract
Previous studies have provided conflicting results on the presence of hepatitis C virus-RNA in saliva. In this study, 23 (62%) of 37 patients tested positive for hepatitis C virus-RNA in saliva, using polymerase chain reaction analysis. A slightly greater proportion had a sporadic rather than a parenteral origin of chronic hepatitis C. These results provide a biological basis for saliva as a possible source of hepatitis C virus (HCV) infection, but do not necessarily imply transmission by this route.
Medical subject headings
- Hepacivirus
- RNA, Viral
- Saliva