Detection of Epstein-Barr virus DNA in cardiac and aortic tissues from chronic, active Epstein-Barr virus infection associated with Kawasaki disease-like coronary artery aneurysms.
case_series · Level IV
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Abstract
We describe three patients with chronic, active Epstein-Barr virus infection associated with Kawasaki disease-like coronary artery aneurysms. The Epstein-Barr virus genome was detected in three cardiac tissue samples and one aortic tissue sample examined by means of the polymerase chain reaction. These findings suggest that chronic Epstein-Barr virus infection may play a pathogenic role in the development of coronary artery aneurysms.
Medical subject headings
- Aorta
- Coronary Aneurysm
- DNA, Viral
- Herpesvirus 4, Human
- Infectious Mononucleosis
- Mucocutaneous Lymph Node Syndrome
- Myocardium