Enhanced urinary excretion of leukotriene E4 in patients with mevalonate kinase deficiency.
case_control · Level III
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Abstract
In patients with mevalonate kinase deficiency, urinary excretion of the leukotriene LTE4 was found to be elevated. A positive linear relationship between increased urinary excretion of mevalonate and LTE4 (n = 5) suggests that increased cysteinyl leukotriene synthesis is involved in the pathomechanisms of this disease.
Medical subject headings
- Phosphotransferases
- Phosphotransferases (Alcohol Group Acceptor)
- SRS-A