Human herpesvirus-6 and Epstein-Barr virus genome in primary cerebral lymphomas.
case_series · Level IV
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Abstract
Using dot blotting, we found Epstein-Barr virus genome in three AIDS-related primary cerebral lymphomas (PCLs), but in none of 39 sporadic PCLs. Human herpesvirus-6 sequences were present only in one sporadic PCL, as revealed by polymerase chain reaction and Southern analysis. We conclude that these viruses do not appear to play a major role in PCL pathogenesis in immunocompetent subjects.
Medical subject headings
- Brain Neoplasms
- Genome, Viral
- Herpesvirus 4, Human
- Herpesvirus 6, Human
- Lymphoma, AIDS-Related