Molecular analysis of the microtubule motor dynein.

Vallee, R · Proc Natl Acad Sci U S A · 1993

review · Level V

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Abstract

Dynein is a large enzyme complex that has been found in recent years to be responsible for a variety of forms of intracellular movement associated with microtubules. Molecular analysis of several of the polypeptide components of dynein and a related complex has provided important new insight into their structural organization and mechanism of action in the cell.

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