Pharmacological bridge to cardiac transplantation: current limitations.

Loisance, D Y; Deleuze, P H; Houel, R; Benvenuti, C; el Sayed, A; Mazzucotelli, J P; Tarral, A; Saal, J P et al. · Ann Thorac Surg · 1993

case_series · Level IV

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Abstract

Addition of intravenous enoximone to sympathomimetic agents permits a rapid and drastic improvement in the clinical and hemodynamical condition of patients in cardiogenic shock referred for a mechanical bridge to transplantation. The present experience, based on the management of 52 patients, permits us to point out the current limitations of this pharmacological bridge: the rate of sudden death, the incompleteness of the physical rehabilitation of the patients, and the vanishing effect of intravenous enoximone.

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