Osteocalcin levels in maternal and cord blood.

Seki, K; Makimura, N; Mitsui, C; Nagata, I · Obstet Gynecol · 1993

cross_sectional · Level IV

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Abstract

To measure osteocalcin levels in fetal and maternal blood. Osteocalcin was measured by radioimmunoassay in paired maternal and umbilical venous and arterial blood obtained at term deliveries. Umbilical venous osteocalcin levels (mean +/- standard deviation) were significantly higher than arterial levels (10.28 +/- 4.99 versus 3.85 +/- 2.27 micrograms/L). Umbilical venous but not arterial levels of osteocalcin were significantly higher than maternal values (2.54 +/- 1.19 micrograms/L). Higher osteocalcin levels in umbilical venous blood than in umbilical arterial blood suggest that the placenta may be the main source of osteocalcin in late fetal life.

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