Mitotic activity in expanded human skin.
case_series · Level IV
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- Record sourced from PubMed, PMID 8430134.
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Abstract
In 20 patients subjected to breast reconstruction by means of tissue expansion, a skin biopsy was obtained at the vertex of the breast before and the day after expansion. Samples were incubated in [3H]thymidine, and the number of labeled cells were counted. A statistically significant rise in the number of labeled basal and suprabasal keratinocytes was seen after expansion. The findings suggest a net gain of tissue not only by stretching but also by formation of new tissue generated by tissue expansion.
Medical subject headings
- Mitosis
- Skin
- Tissue Expansion