Preparation of autologous fibrin glue from pericardial blood.

Kjaergard, H K; Weis-Fogh, U S; Thiis, J J · Ann Thorac Surg · 1993

basic_science · Level V

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Abstract

To salvage patients' blood and improve hemostasis in cardiac operations, autologous fibrin glue was prepared in a new way by means of ethanol from pericardial blood. The yield from 44 mL of blood was 2.1 +/- 0.7 mL (mean +/- standard deviation) of fibrinogen concentrate with a concentration of 25.1 +/- 7.5 mg/mL; 2.7 mL of two-component glue was obtained after the addition of thrombin solution. The glue has the advantages of safety from transmission of viral diseases and from immunologic reactions.

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