Microvascular abnormalities in the mucosal prolapse syndrome.
case_series · Level IV
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- Record sourced from PubMed, PMID 8432438.
- Also identified by PMC identifier 1374110.
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Abstract
Twenty two cases of colorectal mucosal prolapse from a variety of clinical situations were examined histologically to identify changes in the microvasculature which may predispose to ulceration. The findings were compared with 10 tubular adenomas and 10 hyperplastic polyps. Fibrin insudation into vessel walls and thickened mucosal vessels were significantly associated with the presence of ulceration. Possible mechanisms of ulceration are discussed, and an hypothesis based on a microvascular pathogenesis is presented.
Medical subject headings
- Intestinal Mucosa
- Rectal Diseases
- Rectum