Radiotherapy after ovarian transposition: ovarian function and fertility preservation.
retrospective_cohort · Level III
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Abstract
The outcome of ovarian function preservation and fertility after ovarian transposition was examined in women treated for cancer. Of 134 patients, 126 were treated with radiotherapy and 72 with chemotherapy. In a multivariate analysis, three factors appeared to be prognostic of ovarian castration: the age over 25, MOPP chemotherapy and a total dose to the ovaries higher than 5 Gy. The incidence of birth was lower in the general population but no abnormality was observed.
Medical subject headings
- Fertility
- Neoplasms
- Ovary