Dermatitis in treated maple syrup urine disease.

Koch, S E; Packman, S; Koch, T K; Williams, M L · J Am Acad Dermatol · 1993

case_report · Level V

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Abstract

Two children who had classic maple syrup urine disease developed an eruptive dermatitis when plasma isoleucine levels, leucine levels, or both fell below normal during periods of protein restriction. The dermatitis was resistant to topical corticosteroid therapy. Rapid resolution occurred after treatment with isoleucine and leucine dietary supplements.

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