Collagenous colitis: are bacterial cytotoxins responsible?
case_report · Level V
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- Record sourced from PubMed, PMID 8438843.
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Abstract
In a case of collagenous colitis, cholestyramine treatment resulted in symptomatic and histological normalization. After discontinuation of cholestyramine, collagenous colitis relapsed. At this time fecal cytotoxic activity was demonstrated in McCoy cell lines. Symptoms, histologic changes, and cytotoxicity disappeared when cholestyramine treatment was reinstituted. We hypothesize that a bacterial toxin is responsible for the development of collagenous colitis.
Medical subject headings
- Bacterial Toxins
- Colitis