Urinary endothelin-1: not a useful marker for preeclampsia.

Barton, J R; Sibai, B M; Whybrew, W D; Mercer, B M · Am J Obstet Gynecol · 1993

case_control · Level III

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Abstract

Urinary endothelin-1 levels were assayed from 50 gravidas with preeclampsia and 11 with normotension in the third trimester of pregnancy. Urinary endothelin-1 levels (mean +/- SEM) were similar between gravidas with normotension and preeclampsia (62.7 +/- 7.5 vs 79.8 +/- 9.3 fmol/mg urinary creatinine, respectively). Urinary endothelin-1 excretion is not significantly increased in patients with preeclampsia and therefore not a good marker for preeclampsia.

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